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We therefore measured the serum concentrations of total and free testosterone and of sex hormone-binding globulin (SHBG) and determined the androgen receptor () gene CAG repeat length, then compared these values to total and free PSA concentrations in 91 subjects with proven fertility, and 112 subfertile men with defective spermatogenesis.

Concentrations of free testosterone and total testosterone, adjusted for SHBG, were 17–20% lower in subfertile men compared with those in their fertile counterparts.

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The countermovement jump (CMJ) is commonly used to explore sex differences in neuromuscular function, but previous studies have only reported gross CMJ measures or have partly examined CMJ phase characteristics.

The CMJ distinguished between sexes, with men demonstrating greater JH through applying a larger concentric impulse and, thus, achieving greater velocity throughout most of the concentric phase, including take-off.

The countermovement jump (CMJ), performed either with or without an external load, is commonly used both as part of athlete training programs to promote the development of lower body power [1,2,3] and athlete testing batteries to provide insight into neuromuscular function [4,5] and fatigue [6,7,8].

Secondly, in such a low androgenic environment, short CAG tracts (associated with high AR activity) correlate positively with PSA concentrations.

G6PD is the rate-limiting enzyme for PPP activity, which has been reported to be four times greater in female than male bovine blastocysts (Tiffin ., 2001).Male MET-offspring showed increased fetal weight during late pregnancy but decreased live weight postnatally, with compensatory transcriptional responses comprising myogenic key drivers ( and Insulin-like Growth Factor-signaling.These findings in an animal model suggest that supplementation during pregnancy with methylation-related micronutrients can promote sex-specific myogenic maturation processes related to organismal growth and muscle metabolism.It is assumed that bound hormones cannot exit blood capillaries and are therefore not bio-available, and so SHBG concentrations are commonly measured as a supplement to total testosterone determinations (Cunningham ., 1985).The measurement of unbound free testosterone has been proposed as a better measure of bio-active testosterone (Hayes, 2000).This subtle, but highly significant ( = 0.011) with AR CAG length.Overall our data suggest that, firstly, PSA correlates with testosterone only in an environment of relatively low androgenicity, such as in subfertile men.Here, a porcine model was used to assess effects of maternal supplementation with one-carbon-cycle compounds during prenatal and postnatal stages on offspring muscle development.Sows received either a standard diet (CON) or a standard diet supplemented with folate, B6, B12, methionine, choline, and zinc (MET) throughout gestation.The usage of maternal dietary supplements should be more carefully considered regarding its ability to promote fetal and postnatal health.Micronutrients involved in processes related to DNA methylation (e.g., folate, vitamins B6 and B12, methionine, choline, zinc) are commonly provided as supplements during pregnancy to benefit offspring development.Sponsored Products are advertisements for products sold by merchants on When you click on a Sponsored Product ad, you will be taken to an Amazon detail page where you can learn more about the product and purchase it.Jump height (JH), reactive strength index modified, relative peak concentric power, and eccentric and concentric displacement, velocity, and relative impulse were all greater for men ( = 0.58–1.79).Relative force-time curves were similar between sexes, but relative power-, velocity-, and displacement-time curves were greater for men at 90%–95% (immediately before and after peak power), 47%–54% (start of eccentric phase) and 85%–100% (latter half of concentric phase), and 65%–87% (bottom of countermovement and initial concentric phase) of normalized jump time, respectively.




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